Innovative quantum photonic measurement technology for neonatal catheter positioning
EEL sub-project: Magnetic-field-coded positioning for quantum-sensor-based catheter navigation
Project duration: 09/2026 – 08/2029
In preterm infants, catheter insertion is always necessary when the baby is unable to be breastfed due to its immaturity. Correct and complication-free catheterisation is challenging, as the anatomical structures are very small and the heart and respiratory rates are still comparatively high. To assist with this, positioning can be carried out using ultrasound guidance based on anatomical landmarks. However, the visibility of the catheter is not always sufficient due to the limitations of ultrasound technology. The NeoQKat project addresses this problem with a novel technology for electromagnetic catheter tracking based on purely quantum-optical magnetic field sensors. New photonic approaches are intended to make the technology considerably more precise and robust. A novel aspect here is the incorporation of the quantum mechanical transition probability via the fluorescence lifetime of the NV centres. Additional conversion materials, such as ruby or phosphor, are to be used as further measurement parameters. This is intended to enable a metrological distinction between temperature and magnetic field strength, independent of the absolute intensity of the excitation light. A special ultrasound transducer generates magnetic fields in different spatial directions. These fields, which penetrate the body from the outside, are measured by the sensor at the tip of the catheter. The position of the catheter tip is calculated in relation to an ultrasound transducer and visualised in the corresponding ultrasound image. This aids sonography-guided puncture or allows for simple subsequent position verification. NeoQKat thus fills a diagnostic gap in routine clinical practice, as no catheter-tracking systems for preterm infants have existed to date.
The aim of the EEL working group’s sub-project is to develop and experimentally validate a novel method for the precise localisation of catheters in preterm infants. To this end, based on clinical requirements, the necessary physical and technical system parameters, as well as requirements for magnetic field generation, quantum sensor technology, measurement electronics and signal processing, are derived using simulation.
Building on this, suitable magnetic field sources and control concepts will be developed, experimentally characterised and compared with the simulation models. The models for describing and reconstructing complex magnetic fields will be continuously optimised in the process.
As the project progresses, the developed components will be integrated into a prototype setup. This comprises the magnetic field excitation, the quantum sensor, the measurement and evaluation electronics, and the model-based position reconstruction. The experimental setup will first be validated under controlled laboratory conditions and subsequently tested in a real-world environment. The achievable positional accuracy, robustness against interference and the reproducibility of localisation will be experimentally evaluated. The results will serve to scientifically validate the novel localisation method and form the basis for its further development into a clinically applicable catheter-tracking system as part of the collaborative project.
Project partners
- Leipzig University Hospital, Innovation Centre for Computer-Assisted Surgery (ICCAS)
- Martin Luther University Halle-Wittenberg, Centre for Diagnostic and Interventional Ultrasound
- Friedrich Schiller University of Jena
- Leibniz Institute for Surface Modification e.V.
- duotec GmbH
- Quantum Technologies GmbH
Associated partner:
Contact
Prof. Dr.-Ing. René Sallier
Chair of Electronics and Analogue Circuit Technology
Telephone: +49 (0)341 3076 1184
Email: rene(dot)sallier(at)htwk-leipzig.de

Dipl.-Ing. (FH) Michael Eiserbeck
Research Assistant
Telephone: +49 (0)341 3076 1136
Email: michael(dot)eiserbeck(at)htwk-leipzig.de

Dipl.-Ing. (FH) Daniel Käßler
Research Assistant
Telephone: +49 (0)341 3076 1278
Email: daniel(dot)kaessler(at)htwk-leipzig.de
M.Sc. Jens Voigt
Wissenschaftlicher Mitarbeiter
Telefon +49 (0)341 3076 1020
E-Mail: jens(dot)voigt(at)htwk-leipzig.de





